So, a few weeks ago, I was idly paging through my copy of the Aliens Colonial Marine Technical Manual, when I began reading the chapter dealing with Synthetics. Synthetics, in "Alien" terminology, are biological androids. Ash (from the original film) and Bishop (from the second) are both synthetics.
As I read, I said to myself, "Huh - organic androids. Kinda like Replicants in 'Blade Runner'."
What if one were to ignore the opening placard in "Blade Runner," and assume that, instead of Los Angeles of 2019, it was actually Los Angeles, 2219 or so? What if a Blade Runner was called in to deal with a group of Replicants/Synthetics who had broken with their corporate employers - Weyland-Yutani - and were now loose on Earth? What if, in the course of tracking down the Replicants, said Blade Runner discovered that they were trying to stop a Weyland-Yutani cargo from making earthfall, or were trying to destroy one of their biotech research and development facilities that was dealing with off-world organic materials?
If you know what I mean.
I probably don't have to go into what it might be like if said Blade Runner were to learn that Something Else was also looking around for the same xenoform...